DBT Call for Proposals: Microbiome-Based Therapeutics and Translational Opportunities

The Department of Biotechnology (DBT) has invited research proposals under the theme “Microbiome and Their Implications to Human Health and Disease: Therapeutic Potential and Translational Opportunities.”

The initiative aims to move microbiome research beyond descriptive and association-based studies towards functional and translational applications, including probiotics, prebiotics, postbiotics and next-generation biotherapeutics.

Eligible Research submit their proposals online by 15 October 2026.

Explore more Call for Proposals

ParticularDetails
Funding AgencyDepartment of Biotechnology (DBT), Government of India
Call ThemeMicrobiome and Their Implications to Human Health and Disease
FocusTherapeutic Potential and Translational Opportunities
Project DurationUp to 3 years, extendable by 2 years
Submission ModeDBT eProMIS portal
DivisionPublic Health and Nutrition Division
Last Date15 October 2026

Focus Areas

The DBT has identified several areas for development of microbiome-based biotherapeutics:

1. Microbiome-Based Interventions

Proposals may focus on the development of:

  • Probiotics
  • Prebiotics
  • Postbiotics
  • Synbiotics
  • Other microbiome-based interventions

These interventions may target the prevention or treatment of non-communicable diseases, including:

  • Obesity
  • Diabetes
  • Metabolic syndrome
  • Non-Alcoholic Fatty Liver Disease (NAFLD)
  • Urinary tract diseases
  • Neurological and neuropsychiatric disorders

2. Skin-Related Diseases

The call also supports the development of microbiome-based biotherapeutics targeting skin-related diseases.

3. Mycobiome-Based Therapeutics

Another focus area is the development of mycobiome (fungal microbiome)-based biotherapeutics targeting fungal diseases.

4. Microbiome-Based Biomarkers

Proposals can also address the development of microbiome-based biomarkers for:

  • Disease prediction
  • Early diagnosis
  • Risk stratification

Who can Apply?

Proposals are invited from Investigators from the recognized Academic Institutions, Universities/Colleges, National Laboratories, Medical Institutions and Research Organizations recognized by DSIR.

The investigator must hold a regular position in the institution.

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